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Archive for July, 2010

Herbal Allergy Treatment

31 Jul

Herbal Allergy Treatment

Many medicines common to us today were originally discovered in their natural state and then synthesized in the laboratory. Penicillin is one that we have all heard of and there are so many others. Pharmaceutical research scientists to this day explore places like the Amazon Jungle, still looking for more beneficial substances to take back to the laboratory for study. Their goal is to make discoveries, learn to synthesize and then patent to protect their profits. Their is and always has been medicinal substances in their natural state available for those who choose to use them. Commonly known as herbal medicines.

The Food an Drug Administration has consistently worked with drug companies to enact laws and regulations that make it difficult and sometimes illegal for allergy sufferers to obtain alternatives to the drugs distributed by the corporate drug cartels. It is up to you to educate yourself about herbal allergy relief products. Allergy sufferers have to rely on each other in this area of research and discovery. There are many traditional pharmaceutical products out there on the market that work well. The problem for us is that pharmaceutical companies have share holders who have profits in mind. They don’t want us to theirs and only their products.

Herbal allergy relief products have always been here and have always been used. They are nothing new. Long before modern medicine pushed herbal medicines aside, people everywhere relied on herbal medicines. They are in fact are being rediscovered in a way and are now available for anyone who wishes to obtain the benefits they can give. Your allergies are, with the exception of chemical intolerance, caused by natural substances, with a few exceptions. Mold, pollen, dust, and the list goes on and on, are all natural substances. It only stands to reason that if a natural substance is causing the problem then natural herbal allergy relief products can provide relief.

It is not recommended that you start experimenting on yourself. Herbal medicines can and many times do have a high level of potency. Just because something doesn’t come in a pill does not mean it cant contain powerful substances. Always consult an expert before you begin using herbal allergy relief products or any other herbal medicine for that matter. What works for someone els may not necessarily work for you. So picking up and trying something that someone has told you has worked for them could only increase your suffering. So do your own research, consult an expert on homeopathy and find out what is best for you before you begin using herbal allergy relief products.

So in the end the choice is your own. You are the one doing the suffering. If you are not entirely satisfied with your treatments in the past. Or if you would just like to see more improvement in your allergy relief. Then look into the option of herbal allergy relief products. It is not recommended that you throw down your prescription medicine and stop using them. Most work very well and are a necessity for many allergy sufferers. But used in conjunction with your other allergy medicines, herbal allergy relief products can provide that extra relief you have been hoping for. Many people have found complete relief with herbal allergy relief products and have been able to say good-bye to chemically synthesized drugs for good.

 
 

Molecular Study On Azotobacter Nif H Gene By Pcr

31 Jul

Molecular Study On Azotobacter Nif H Gene By Pcr

Introduction
Nitrogen fixation is the reduction of N2 (atmospheric nitrogen) to NH3 (ammonia). Free living prokaryotes with the ability to fix atmospheric dinitrogen (diazotrophs) are ubiquitous in soil. But our knowledge of their ecological importance and their diversity remains incomplete. In natural ecosystems, biological N2 fixation is most important source of N. The capacity for nitrogen fixation is widespread among bacteria and archaea. The estimated contribution of free-living N-fixing prokaryotes to the N input of soil ranges from 0-60 kg/ha /year (Burgmann et al., 2003). Dinitrogen (N2)-fixing microorganisms (diazotrophs) play important roles in ocean biogeochemistry and plankton productivity (Church et al., 2005).

Nitrogen fixation can be an important source of nitrogen for biological productivity in the marine environment. Biological nitrogen fixation is catalyzed by the enzyme nitrogenase, which is possessed by diverse microorganisms representing virtually all phylogenetic groups. Interest in nitrogen fixation in the sea has usually been focused on rates of nitrogen fixation, but information on the types of species present with the capability for nitrogen fixation can be important for predicting nitrogen fixation rates in situ (Zehr et al., 1998).

Nitrogenase catalyzes the reduction of nitrogen gas to ammonium in an ATP-and reductant dependent reaction. It is one of the best characterized metalloenzyme and is an excellent model for elucidating metalloprotein assembly. Nitrogenase is composed of two oxygen-labile metallo protein; dinitrogenase and dinitrogenase reductase. Dinitrogenase is a 240-KDa alpha2-beta2 tetramer of the nifD and nifK gene products. Dinitrogenase reductase is a 60-KDa alpha2 dimer of the nifH gene products that contains a single 4Fe-4S center coordinated between the two subunits (Rubio et al., 2005). Understanding how fixed N regulates nitrogenase availability is necessary for devising strategies to increase the amount of ammonium synthesized by nitrogen fixing bacteria with the potential to be used in agriculture (Kennedy et al., 2004).

Molecular tools for detection and characterization of the nitrogenase (Nif) genes and immunoassays for nitrogenase protein can provide new information on the factors regulating the distribution and activity of diverse nitrogen fixing organisms in the marine environment. Amplification and characterization of NifH sequences has made it possible to identify the type(s) of organism responsible for nitrogen fixation, such as in aggregates of the cyanobacterium and Trichodesmium. Differences in nitrogen fixation patterns have been linked to genetic differences between Trichodesmium strains. Further development of these approaches will provide new and powerful ways to link the genetic potential for nitrogen fixation to nitrogen fixation rates in the ocean (Zehr et al., 1998)

Nitrogenase gene (NifH) sequences amplified directly from oceanic waters showed that the open ocean contains more diverse diazotrophic microbial populations and more diverse habitats for nitrogen fixers than previously observed by classical microbiological techniques (Zehr et al., 1998). Understanding how fixed N regulates nitrogenase availability is necessary for devising strategies to increase the amount of ammonium synthesized by nitrogen fixing bacteria with the potential to be used in agriculture (Kennedy et al., 2004).

The commercial history of biofertilizer began with the launch of “Nitrogin” by Nobbe and Hiltner; a laboratory culture of rhizobia in 1895, followed by the discovery of Azotobacter and then the blue green algae and a host of other microorganisms. Azotobacter is used as a biofertilizer in the cultivation of most crops. Azotobacter is an obligate aerobic diazotrophic soil-dwelling organism with a wide variety of metabolic capabilities, which include the ability to fix atmospheric nitrogen by converting it to ammonia. Azotobacter naturally, fixes atmospheric nitrogen in the rhizosphere. There are different strains of Azotobacter each has varied chemical, biological and other characters. However, some strains have higher nitrogen fixing ability than others (Burgmann et al., 2003). Besides, nitrogen fixation, Azotobacter also produces, Thiamin, Riboflavin, indol acetic acid and gibberellins. When Azotobacter is applied to seeds, seed germination is improved to a considerable extent, so also it controls plant diseases due to above substances produced by Azotobacter (Kader et al., 2002.)

This NifH gene has been largely studied by culture-independent approaches. These approaches provide a more complete picture of the diazotrophic community than culture-based approaches. Various techniques, such as PCR cloning, denaturing gradient gel electrophoresis, PCR-restriction fragment length polymorphism (RFLP), and fluorescently labeled terminal (FLT)-RFLP, have been used to analyze the composition of NifH gene pools in various environments. These studies found that the NifH gene is present in diverse environments: forest soil, the rhizosphere of native wetland species, such as Spartina, or of crop species, such as rice, aquatic or polar cyanobacteria, and the bacteria found in termite guts. All these studies described a large number of unknown sequences which correspond to diverse unidentified diazotrophs. Some NifH genes are characteristic of an ecological niche (Shaffer et al., 2000) evoked the possible relationship between the habitats of soil nitrogen-fixing bacteria and the structure of NifH gene pools (Poly et al., 2001).

Nitrogen fixation in A. vinelandii is complicated by the presence of three biochemically and genetically distant nitrogenase enzymes, each of which is synthesized under different conditions of metal supply. The regulation of conventional molybdenum nitrogenase, whose subunits are encoded by the Nif-HDK genes and which is similar to the enzyme purified from number of other nitrogen-fixing organisms. (Sabra et al., 2000). The Nif-HDK genes are located in a large cluster of nif genes, which includes, in order, NifHDKTYENXUSVWZMF (Bali et al., 1992). Molecular methods based on universal PCR detection of nifH marker genes have been successfully applied to describe diazotroph population in the environment (Burgmann et al., 2003).

Materials and Methods

Sample collection
Samples were collected in different locations of Rameshwaram marine region (Gulf of Mannar) at the depth of 1–5 m. The randomly collected samples in the sterile plastic bags (soil sample) and water sampling bottles (water sample) bottles were kept in an ice-cold box and transported safely to the lab for further analysis with in 12 hrs. The sample with media tubes were packed and transported safely to the laboratory.

Isolation of Azotobacter from water and sediment samples (Mary et al., 1985)
Different selective media were used for the isolation of Azotobacter sp from marine source as described previously. Azotobacter strains used for this study were maintained and cultured in Burk medium as previously described (Joerger et al., 1988). As the isolates are of marine origin, the media were prepared by the 3.5% sodium chloride (NaCl). Media used for the isolation of nitrogen fixing organism (Azotobacter) from marine sources were Jensen’s agar medium, Azotobacter agar medium, Burk’s Medium and marine agar medium.

Culture characteristics (Bagwell et al., 1988)
Gram-staining characteristics and cell morphologies were determined by standard methods(Gerhardt et al., 1981). Motility was observed in wet mount using phase contrast microscope. Preliminary physiological characterization such as catalase test, starch hydrolysis test were also carried out.

Extraction and purification of DNA (Kelly et al ., 1990)
Azotobacter genomic DNA was isolated as previously described (Robson et al., 1980). Linear DNA fragments were analyzed by electrophoresis in agarose gel in TEB buffer (Maniatis et al., 1982). The purity of the DNA was checked spectrophotometric method by using the formula OD at 260 nm/ OD at 280 nm (Wilfinger et al., 1997).

PCR amplification of the NifH gene fragment

Nitrogenase Fe protein genes (NifH) were amplified from Azotobacter sp derived genomic DNA, using the primer from OPERON diagnostic Ltd, USA. The samples were amplified by PCR in a mixture containing reaction buffer 5.0 µl, 10mM dNTP 1.0 µl, primer 1 (25 mer) 1.0 µl, primer 2 (24 mer) 1.0 µl, template DNA 1.0 µl, enzyme Taq polymerase 1.0 µl for 35 cycles ( 1 min at 94° C,1 min at 54° C and 1 min at 72° C) (Zehr et al., 1988).

Results and Discussion
Totally 100 samples were collected in marine region of both water and sediments in the intervals of approximately 20 days .Out of 70 marine water samples collected, all the 70 samples were showing the presence of Azotobacter, but only 23 marine sediments out of 30 were showing the presence of Azotobacter. These samples were processed through the commonly used procedures such as selective media. Gram’s staining, Phase contrast observation for motility, starch hydrolysis test and Catalase test for identification of free- living diazotrophic organism i.e Azotobacter from the above samples, and that can be processed, result shows that Azotobacter sp are motile, gram negative, catalase and starch hydrolysis positve.

The colony morphology of Azotobacter strains were varying during the isolation in the selective media. The colonies were very clear, large, mucoid, watery due drops like initially i.e. from the marine source. The mother culture was sub cultured in the same media; the colony morphology differs slightly i.e. small, and circular, convex in nature. All the isolated Azotobacter strains were numbered for the easy identification and convenience. From these isolates, well defined pure culture of Azotobacter strains (1, 16, 27, 82, 101, 103, 108, 115, 125, and 132) were selected for the nucleic acid analysis.

The reference (standard) cultures such as Azotobacter beijerinckii (123), A. chroococcum (446), and A. vinelandii (124) procured from MTCC, (Chandigarh, India) were also used along with marine isolates for the nucleic acid extraction and purification. The DNA of the selected strains was isolated and estimated OD at 260 nm, the value ranges from 0.141 to 0.177. The estimated value of the extracted DNA was ranging from 0.70 to 0.88.The purity of the DNA was analyzed by spectrophotometric method using OD at 260 and OD at 280 nm. The presence and purity of DNA was checked by OD at 260nm/ OD at 280 nm, the value ranges from 1.13 to 2.21. If the estimated value is 1.8 conforms the presence of pure DNA. If the estimated value is lesser /greater than 1.8 conforms the presence of DNA to protein / RNA contamination, according to respective values DNA was purified using the enzymes proteases and RNase. The purified form of the DNA was separated by the agarose gel electrophoresis for the comparison the banding pattern between the randomly selected marine samples and the standard strains. There is no substantial difference between the banding patterns of the chromosomal DNA on the gel as shown in the plates. This result confirms that molecular weight of chromosomal DNA in all strains is similar.

One µl of DNA was used as template in PCR. selected primers, primer1:5-GGAATTCCTGYGAYCCNAARGCCNA-3,
Primer2:5-CGGATCCGDNGCCATCATYTCNCC-3 procured from OPERON diagnostics LTD, USA, respectively was used to amplify a 324-bp region between sequence positions 336 and 660. All N2 fixers carry a NifH gene, which encodes the Fe protein of the nitrogenase (Poly et al., 2001). The results of the PCR products were compared on 2% agarose gel electrophoresis. Selective NifH primer from Anabaena sp strain PCC7120 was used for the amplification of the Azotobacter sp, the primers used in my study was exactly matching the Azotobacter genome. Free-living nitrogen-fixing prokaryotes (diazotrophs) are ubiquitous in soil and are phylogenetically and physiologically highly diverse. Molecular methods based on universal PCR detection of the NifH marker gene have been successfully applied to describe diazotroph populations in the environment. However, the use of highly degenerate primers and low-stringency amplification conditions render these methods prone to amplification bias, while less degenerate primer sets will not amplify all NifH genes (Bürgmann et al., 2003).

References

Bagwell, C.E., Piceno, Y.M., Lucas, A.M. and Lovell, C.R., 1988. Physiological diversity of the rhizosphere diazotroph assemblages of selected salt marsh grasses. Appl. Environ. Microbiol., 64(11): 4276-4282.
Bali, A., Gonzalo Blanco, Susan Hill, and Christina Kennedy 1992. Execretion of Ammonium by a NifL Mutant of Azotobacter vinelandii Fixing Nitrogen. Appl. Environ. Microbiol., 58(5 ): 1711-1718.
Bürgmann H, Franco Widmer, William Von Sigler, and Josef Zeyer. New Molecular Screening Tools for Analysis of Free-Living Diazotrophs in soil. Environmental Microbiology, Vol.70, No1 p.240 – 247.1999.
Bürgmann H, Manuel Pesaro, Franco Widmer and Josef Zeyer strategy for optimizing quality and quantity of DNA extracted from soil. Bacteriological Reviews, vol.36, No.2 p.295-341. 2003.
Church M J, Cindy M. Short, Bethany D. Jenkins, David M. Karl, and Jonathan P. Zehr, Temporal Patterns of Nitrogenase Gene (NifH) Expression in the Oligotrophic North Pacific Ocean’ Ocean Sciences Department, Environmental Microbiology, Vol 134, No.1 p.155-193, 1999.
Gerhard,P.,R.G.E.Murray,R.N.Costilow,E.W.Nester,W.A.Wood,N.R.Krieg,andG.B.phillips.1981.Manual of method for generalbacteriology.American SOCIETY FOR microbiology, Washington, D.C.
Joerger, R.D., Jacobson, M.R., Premakumar, R., Wolfinger, E.W. and Bishop, P.E., 1989. Nucleotide sequence and mutational analysis of the structural genes (anfHDGK) for the second alternative nitrogenase from Azotobacter vinelandii. J. Bacteriol., 171(2): 1075-1086.
Kader.M.A, Mian.M.H, Hoque.M.S. Effect or Azotobacter inoculant on the yield and nitrogen uptake by wheat. Department of soil science, Bangladesh Agricultural University, Mymensigh, Bangladesh. Vol 2(4) p 251-261,2002.
Kelly, M.J.S., Poole, R.K., Yates, M.G. and Kennedy, C., 1990. Cloning and mutagenesis of genes encoding the cytochrome bd terminal oxidase complex in Azotobacter vinelandii: mutants deficient in the cytochrome d complex are unable to fix nitrogen in air. J. Bacteriol., 172(10): 6010-6019.
Kennedy.C, R.K.Poole, M.G.Yates, and M.J.S.Kelly. Cloning and Mutagenesis of Genes Encoding the Cytochrome bd Terminal Oxidase Complex in Azotobacter vinelandii: Mutants Deficient in the Cytochrome d Complex are unable To Fix Nitrogen in Air.Journal of Bacteriology, Vol.172,No.10 p.6010-6019 . 1990
Maniatis,T.,E.F.Fritsch,and J.Sambrook.1982. Molecular cloning: a laboratory manual. Cold spring Harbour Laboratory,Cold Spring Harbor,N.Y
Mary. L. G and rita r. colwell, Enumeration ,isolation and characterization of N2 fixing bacteria from sea water . Department of microbiology, University of Maryland. Vol 50 no .2. 1985
Poly .F, Lionel Ranjard, Sylvie Nazaret, François Gourbière, and Lucile Jocteur Monrozier.. Comparison of NifH Gene Pools in Soils and Soil Microenvironments with Contrasting Properties in Applied and Environmental Microbiology Vol. 67 p. 2255-2262. 2001
Robson,R.L.,J.A.Chesshyre,C.Wheller,R.Jones,P.R.Woodley, and J.R.Postgate. 1984.Genomic size and complexity in Azotobacter chroococcum.J.Gen Microbial.130:1603-1612.
Rubio .L M, singer.S.W, and Ludden P.W. Purification and Characterization of NafY from Azotobacter vinelandii. Department of plant and microbiology,college of natural resources, University of California, California. 2005
Sabra, W., Zeng, A.P., Lunsdorf, H. and Deckwer, W.D., 2000. Effect of oxygen on formation and structure of Azotobaceter vinelandii alginate and its role in protecting nitrogenase. Appl. Environ. Microbiol., 66(9): 4037-4044.
Shaffer, B. T., F. Widmer, L. A. Porteous, and R. J. Seidler. Temporal and spatial distribution of the NifH gene of N2-fixing bacteria in forests and clear-cut in western Oregon. Microb. Ecol. 39 P.12-21. 2000.
Wilfinger W.,Mackey K. and Chomczynski P.1997 Effect of Ph and ionic strength on the spectrophotometric assessment of nucleic acid purity. Bio Techniques,22,474-481.
Zehr .J. P ,Mark T. Mellon, and Sabino Zani. New Nitrogen-Fixing Microorganisms Detected in Oligotrophic Oceans by Amplification of Nitrogenase (NifH) Genes. 1998.
Zehr .J. P. Sarah Braun, Yibu Chen and Mark Mellon Nitrogen fixation in the marine environment: relating genetic potential to nitrogenase activity. Department of Biology, Rensselaer Polytechnic Institute, Troy, NY 12180-3590, USA . 1999.

Karthick.A* and Jayashree, V.S
Dr.G.R. Damodaran College of Science
Coimbatore

* Corresponding address

Dr.G.R. Damodaran College of Science,
Avanashi road ,civil aerodrome post,
coimbatore 14

 
 

Seven Ingredients That Identify The Best Skin Care Products

31 Jul

Seven Ingredients That Identify The Best Skin Care Products

As we age, our skin (epidermis) loses elasticity and becomes less supple. We develop wrinkles, age spots, our skin becomes drier and in need of additional hydration. Finding the best skin care products becomes increasingly important as we age, particularly the anti-aging skin care variety.


As we get older, our body produces less collagen which is necessary to maintain skin elasticity. This deficit is what causes our skin to wrinkle and sag. The skin discoloration that often accompanies aging skin is due to decreased oil production and increased drying of the skin as a result of sebaceous glands that no longer work well.


The purpose of an anti aging skin care regime is to re-hydrate the skin and keep it as youthful as possible for as long as possible.


The commercial skin care industry abounds with anti-aging skin care products and special formulations to revitalize aging skin. However, there are so many anti-wrinkle skin care creams and lotions for mature skin that it can be difficult to sort through them all to find the best preparations.


An effective way to compare brands is to consider their ingredients. If you know what specific ingredients can do for your skin you can read the labels and get a good idea of the likely effectiveness of particular formulations.


Here are seven of the most effective anti-aging skin care ingredients that can be included in facial skin creams:


1. Idebenone – Coenzyme Q10 or CoQ10 (also known as ubiquinone) is a powerful antioxidant which has been chemically synthesized into Idebenone which also has strong antioxidant properties. CoQ10 was synthesized because it was found to reduce the risk of heart disease and free radical damage as well as impeding the development of some nervous system and neurological disorders.


This natural enzyme was synthesized in an attempt to increase its effectiveness. Initially, it was taken internally and was found to increase brain function, energy levels, nerve growth factor and serotonin as well as protecting cells and reducing inflammation. There are no known adverse side effects of using this drug.


More recently, skin care manufacturers tested topical versions of Idebenone on damaged skin and found that it was very effective in preventing and even reversing free radical damage caused by sun exposure, diet and lifestyle. As we age, our body has less ability to fight free radicals so the use of this element and other topical antioxidants in skin care preparations can help the skin cells to regenerate and prevent further deterioration.


2. Edelweiss Extract is another powerful antioxidant which neutralizes free radicals caused by exposure to UV sun rays over time, pollution, and the modern western diet which is high in fats and sugars. Furthermore, it prevents the increase of super oxides which actively promote the aging of skin. It also provides a natural protection against harmful ultraviolet rays also making them excellent additives to sun screens.


Edelweiss extract contains bioflavonoids which help to strengthen blood vessel walls. It is therefore an excellent ingredient for wrinkle reduction creams and lotions.


3. Evening Primrose Oil has been used throughout history to treat a variety of ailments. In particular, it reduces inflammation and heals eczema, psoriasis and dermatitis. Where anti-aging skin care products are concerned, Evening Primrose’s ability to reduce skin inflammation is particularly important. The oil of the evening primrose contains seventy eight percent essential fatty acids and is linoleic and gamma linolenic acids. These components maintain the skin’s water barrier and nurture the membranes of skin cells.


Deficiency in Essential Fatty Acids can hasten the aging process of the epidermis by reducing the activity of the sebaceous glands, increase the likelihood of acne, eczema and psoriasis, cause the skin to become dehydrated and weaken the skin’s surface capillaries. The addition of essential fatty acids in topical preparation and internal medications helps to replace those acids that the body loses and cannot produce on its own.


Consequently, the inclusion of Evening Primrose Oil in antiaging formulas is extremely beneficial as it helps to prevent wrinkles, helps the skin to maintain its shape and texture and slows the effects of time process. The best skin care products are likely to contain it.


4. Shea Butter butter naturally moisturizes and tightens the skin. Like edelweiss extract, it also protects the skin from ultra violet light. It is one of the most effective ingredients found in many age defying skin care products. It is not only a moisturizer that makes wrinkles less noticeable and helps skin to appear smoother, it also improves skin elasticity and suppleness, improves skin tone and removes dry, scaly or rough skin.


This interesting additive contains fatty acids which prevent drying, cracking, wrinkling and burning of the skin in addition to assisting in the regeneration and healing of damaged skin. To be a truly effective ingredient in an anti-wrinkle skin care product, it is recommended that the product contains at least twenty percent of Shea Butter.


5. Vitamin A (Retinol) is another extremely important antioxidant which is particularly beneficial. The small molecular structure of this vitamin allows it to penetrate the skin’s epidermis so that it can act to repair damage in the lower layers of skin as well as stimulate them to produce collagen and elastin. It acts to eliminate age spots and improve the pigmentation of the skin.


Vitamin A also helps to regulate the growth of skin cells. Using it topically helps to improve skin elasticity, and smooth skin that is rough, dry or thicker than normal. Retinol is also important for healthy immune function, digestive health and eyesight. Not only should it be included in anti wrinkle creams, it should be taken internally as a nutritional supplement to ensure that aging skin is fully supported.


6. Vitamin E is an antioxidant enhancer and increases the effects of the other antioxidants in an age fighting formulation. It also promotes healing of damaged skin and has been shown to prevent skin cell damage and inhibits the ability of free radicals to damage skin cells.


7. Vitamin C helps to increase collagen production which smooths the skin out and reduces wrinkles. It also improves blood flow which improves the complexion and can enliven dull skin.


If you read the labels on anti-aging formulations carefully and ensure that these ingredients are included, you will be able to distinguish between products and give yourself the best chance of finding the best skin care products to suit your needs.

Ken Black is the owner of www.Skin-Care-Reviews.com, a website all about skin care. Visit us today for more information on Anti Aging Skin Care Products.

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Theory, Fossils, and a Two-sided Puzzle

31 Jul

Theory, Fossils, and a Two-sided Puzzle

Do fossils support evolution? Or do they undermine the theory? Scientists have now scrutinized over 100,000 specimen from around the world covering fauna from the past 3,500,000,000 years. What have they learned? Let’s check it out.

Glimpses from the Past

The fossil record has troubles of its own. See if you can follow this logic: Paleontologists start with the premise that evolution progresses from simple to complex life forms. Thus the simpler the fossil, the older it is. As a result, the fossil is roughly dated according to its complexity.

Paleontologists use the “dated” fossils to establish the age of rock segments in which they are found. Then they turn right around and say, “Look, evolution is a fact. We have a series of increasingly complex forms taken from chronologically dated rock segments to prove it.”

The assumption of evolution is used as proof of evolution! The whole thing reminds you of a dog chasing its tail. Just the same, rock layers occasionally play tricks on the experts. More advanced specimen are found in levels lower than expected, while simpler types show up where they shouldn’t be. These contradictions are dismissed as irregularities or nonconformities.

But if rock layers are sometimes uncooperative, so are the fossils. Geologists, as well as paleontologists, frequently rely on “index fossils” to provide a rough date for rock segments. That procedure gives us ballpark figures as long as the origin and the extinction dates of the index fossils are known. But what happens when the fossil, which has been officially declared dead millions of years ago, suddenly turns up alive?

All the rock segments dated by that fossil have to be reevaluated. This embarrassment has happened all too often. The tuatara lizard, the small mollusk Neopilina galatea, the maidenhair tree, the dawn redwood, and the coelacanth were all thought to be extinct. Now we know better.

Have we ironed out all the knotty little dating problems? Probably not, especially when you consider that most index fossils are small marine organisms, and the ocean depths are still largely unexplored.

Charles Darwin left us with a pretty good metaphor. He compared the fossil record to a book in which only a few scattered pages were preserved; on those pages only a few lines are found; of those few lines, just a few words remain; and of those few words, only a few letters are legible.

That was a very apt description of the fossil record in Darwin’s day. Our picture of the past is somewhat better than it was in the mid 19th century, but it is still limited. Bear in mind when we find anything at all, it is usually a tooth, bone, or shell – or more likely, just part of a tooth, bone, or shell. Most animals, past and present, have no hard parts. Consequently, we are not likely to find any evidence at all for most species.

Occasionally, paleontologists get lucky and find whole specimens preserved intact – soft parts and all. They discover insects in amber or entire communities of creatures encased in a mud slide. Outside of those rather unusual circumstances, we have little or no evidence of most animals’ soft anatomy.

You would think that such a scanty fossil record with all of its limitations and imperfections would be enough to make a paleontologist humble. The fossil record, spotty as it is, still tells us a story we cannot get from any other source. Fossils are our only real evidence of prehistoric life on earth.

Over 100,000 specimen from around the world now provide us with a series of glimpses from the past. An imperfect record to be sure, but it’s the best we have. Here is what the fossil record shows:

Early Fossils: A Two-Sided Puzzle

Precambrian Eon – 3,500,000,000 years ago – Blue-green algae and Bacteria found in 24 locations in western Australia, Africa, and Canada.

These were completely soft-bodied, single-celled organisms, known as prokaryotes. This is a relatively simple type of cell having no organelles, no nucleus, no paired chromosomes, no mitochondria, and no chloroplasts. They reproduce by simple cell division. The cell divides into two identical “daughter” cells. Since the daughter cells are identical to its “parent,” the only way change can come about is if an accident (mutation) affects the genetic material itself.

The difference between prokaryotic cells (blue-green algae, bacteria, and fungi) and eukaryotic cells (all other life forms) is so profound that prokaryotics are classified as a separate kingdom, the kingdom Monera.

Precambrian Eon – 1,500,000,000 years ago – Protistans found worldwide.

These were completely soft-bodied, single-celled organisms, known as eukaryotes. They too have a separate kingdom, called Protista. Some lived by photosynthesis like plants; others fed on food particles like animals; still others did both.

Eukaryotes are larger and much more sophisticated cells than the prokaryotes. Outside of bacteria, blue-green algae, and fungi, every other form of life – protistans, plants, and animals – are composed of eukaryote cells. The difference between the two types of cells is striking. Eukaryote have distinct nucleus with chromosomes containing genetic instructions and a nucleus membrane isolating the genetic material from the rest of the cell.

Moreover, eukaryotic cells include a nucleolus which synthesizes ribosomes: endoplasmic reticulum which transports materials and synthesizes lipids and certain proteins; golgi complex which stores materials and transports them out of the cell and synthesizes carbohydrates; lysomes which break down unwanted molecules; and mitochondri which performs cellular respiration.

What does all of this mean? It means after two billion years of nothing but prokaryotes, we run into an entirely different form of life. Cell by cell you, I, and an oak tree have more in common with a single-celled protistan than the protistan has in common with a bacteria or blue-green algae.

It’s a big leap from a prokaryote to an eukaryote. And there is nothing between. Think of two billion years of seeing nothing but three-piece jazz bands. Suddenly, you encounter a full symphony orchestra. If your theory was that jazz bands evolved into symphony orchestras, you would expect to find a few intermediate-sized bands between the two.

The puzzle remains. If prokaryotes evolved into eukaryotes, why don’t we see a progression of forms? Some reason that since the intermediate forms would be soft bodied, we shouldn’t expect to find any fossilized remains. The obvious reply to this argument is: All the prokaryotes and the protistans were soft bodied too. Yet we have discovered a good number of each intact, whole, and clearly distinguishable from each other. However, we find no transitional cells between the two.

Life in the fossil record is 3.5 billion years old. For 2.8 billion years – 80 percent of life’s fossil history – life apparently did not evolve at all. It stayed on the same level of single-celled organisms, each one carrying on all life’s functions independently. Then around 700 million years ago, multicellular animals began showing up in the fossil record.

Precambrian Eon – 700,000,000 years ago – Ediacara fauna found worldwide.

Ediacara fauna are the first known multicellular animals. These large pancake-flat soft bodied creatures were originally discovered in Australia but the fauna has since been found world wide. They may have been an experiment in multicellular life that failed. Their design matches no modern anatomical plan. By the Cambrian period, all traces of these animals had perished.

Cambrian Period – 525,000,000 years ago – Anemones, Clams, Crustaceans, Jelly Fish, Octopuses, Sea Lilies, Snails, Sponges, Starfish, Trilobites, and Worms. By the end: Corals and Chordates – found worldwide.

Paleontologists call it the Cambrian explosion. In a geological moment just before the beginning of the Cambrian, nearly all modern invertebrate phyla appear suddenly and simultaneously along with an even greater number of anatomical curiosities which did not survive.

Phylum already show their distinct characteristics. Transitional forms are conspicuously absent. Even classes, the taxonomic level below phylum are found in place and very similar to what they are today. At the lowest classification level, more than five thousand species have been discovered in the Cambrian layers.

Surprising? Yes, it is. Evolution is not suppose to work that way. In a geological blink of an eye, we go from single-celled organisms to a vast array of complete, multi-celled animals found worldwide. These animals are fully equipped with intestines, hearts, stomachs, bristles, eyes, and feelers.

The eyes and feelers tell us that complex nervous systems were already intact. Trilobites show a distinctive head and tail, numerous thoracia parts, joint legs, a complex respiratory system, and fully developed compound eyes.

The relatively simple single-celled prokaryote dates back 3.5 billion years; 2,975,000 years later we find the highly complex, multi-celled, multi-organed trilobite. For all practical purposes, everything between the two is a missing link. Did a prokaryote cell evolve into an eukaryote cell? Did an eukaryote cell in turn evolve into the trilobite, sponge, jellyfish etc., of the Cambrian period? The fossil record is completely silent on these subjects.

What we find is a two-sided puzzle. We have explored the first half of that puzzle. Life didn’t evolve. It stayed at the same level of single cells for 2,800 million years. Then after one or possibly two false starts, life exploded into a multitude of radically different, complex creatures.

Equally inexplicable is the flip side of the coin. Over five hundred million years have passed since the end of the Cambrian period, and not a single new animal phylum or basic design has shown up in the fossil record. Something opened the flood gates 525 million years ago, and out poured phyla and classes. The gates remained open for five to ten million years. Then abruptly, they were closed again.

Few new classes and no new phylum have appeared since that time. The last 500 million years have added nothing but variations to the well-established Cambrian designs. Most curious.

One explanation for the Cambrian explosion is that the period merely marks the appearance of shells in the fossil record. Before developing shells, multicellular life may have undergone a long history of gradually increasing complexity, leaving no record in the rocks.

If you will recall, that’s the pretext offered for not finding intermediate stages between prokaryote and eukaryote cells. That line of reasoning ignores all of the soft-bodies fauna gathered from rock segments dated before, during, and after this period.

In fact, soft bodies were the rule – not the exception in the early years of life. Bacteria, blue-green algae, the protistans, and the Ediacara fauna were all soft-bodied types. Even the creatures in the Burgess Shale were partially soft. Yet we find a number of them preserved intact. All of these soft forms defied the odds and found their way into the fossil record.

Bearing all of that in mind, let’s assume for a moment that the theory of evolution is correct. If single-celled eukaryotes took million and millions of years to evolve into jellyfish, trilobites, octopuses, and all of the other five thousand species of the Cambrian period, why haven’t any of those intermediate fossils turned up?

And another question: Why did all the Cambrian fossils, diverse as they are, choose the same geological moment for developing shells?

Here is one possible explanation. No Cambrian fauna predecessors have been found because — there weren’t any. And those shelled fossils all appeared at the same time because that is when those animals came into existence. This interpretation accounts for all the known facts. Moreover, it does not resort to any slight of hand, claiming that all the important evidence is for one reason or another “off the record.”

Jerry Boone, Gatlinburg, Tennessee, United States webmaster@merechristianity.us Mr. Boone is a sailor, author, and webmaster of http://merechristianity.us with a Bachelor of Arts degree in Anthropology from Georgia State University. His works include: Mere Christianity.us and SAFETY LINE – EVIDENCE OF THINGS NOT SEEN, an apologetic study published 1998.

 
 

Herbal Healing (herbs a Natural Remedy to Most Common Ailment)

31 Jul

Herbal Healing (herbs a Natural Remedy to Most Common Ailment)

The use of herbs in the treatment of diseases is probably the oldest form of medicine known to man. By 3,000 BC the ancient Egyptians already had a sophisticated knowledge of different herbs and their properties. Every culture throughout history has used herbs in one form or another to promote health and treat diseases. It has been estimated that even today 75% of the world’s population relies on herbs as the mainstay of treatment.

In the west, the use of herbs declined with the advent of the pharmaceutical industry. Initial, the so-called active ingredient was extracted from herb, and then synthesized in the laboratory. Many were added to and changed. Scientists, Doctors and Pharmaceutical companies believed these chemicals to be superior in every way to the origin herb.

However, the most important aspect of Natural Medicine, that is, that each herb contains many pharmacologically active ingredients, was overlooked in the zealous pursuit of s single drug to counteract every symptom of disease. The presence pf a variety of ingredients in each herb has been shown it enhance and broaden the effect. Combined the different active ingredients work together to make herb far more effective than the synthesized chemical can ever be.

As orthodox medicine battle to cope with tidal wave of chronic diseases and the problem of bacterial resistance to antibiotics, attention has once again been redirected to herbs and natural remedies, a timeless method of healing.

PRODUCT OF NATURAL ORIGIN

The products of natural origin are the source and root of modern medicine and serve as the basis of curing many infirmities as effective home remedies.

In this decade, natural nutrients have taken on an unusual impetus for having been proven day-by-day that they are the answer for healing that is sound, economical and without the many side effects that many other synthetic medications usually have.

The most recent investigations have demonstrated that vitamins, minerals, healing plants, bee products, polyunsaturated fatty acids and other natural product, taken in adequate dosage, produce optimal health and avoid most illnesses, help strengthen the body’s defenses (immune system), and at the same time fight diseases in a direct and effective manner.

Among the plant that are found in nature, there are many the have managed to make an impression within the area of herbalism and natural medicine, of their healing and nutritional properties. As an example we can cite the following;

Aloe Vera. This contains amazing healing properties. It inhibits pain and reduces inflammation. It is excellent as a detoxicant (cleanser), coagulant, cicatrisant, cell regenerator, digester, detoxifier, rehydrator and an energizer. It is highly nutritional as it contains 17 of the 23 amino acids required by the human body for complete health.

Garlic. This belongs to the lily family of plant like aloe Vera. Garlic has served humanity for millenniums with its antibiotic, germicidal, revitalizing, and healing properties.

Honey and Bee Pollen. Both contain the majority of vitamins and minerals that the human body needs for its proper functioning.

Royal Jelly and Bee Propolis. In addition to the essential elements, these contain substances synthesized by the bees. They are of great use for the functioning and regeneration of cell, such as growth hormones, enzymes and vitamins, in addition to other healing properties.

Ginseng. One of the wonderful contributors of the orient has been the ancestral plant. Ginseng, taken to Europe for the first time in the 17th century. It is recognized for it adaptogenic and energizing functions. When combined with Gold Sage or Aloe Vera it produces great therapeutic results.

Garcinia Cambogia. Also from the orient, we have Garcinia Cambogia whose properties help maintain a correct body weight by inhibiting appetite and converting stored fats into energy.

Ginkgo Biloba. This is one plant of unequaled therapeutic value whose endless attributes improve circulation and cerebral activity. Added to the forever Ginkgo plus are the fo-ti plat and the schizandra plant, as well as reshi mushroom which increase longevity and help alleviate problems related to old age by supplying the energy and increasing the life span.

Aloe Vera. The Aloe family of plants includes over 200 varieties. Of this, it is the Aloe Barbadensis Miller (Aloe Vera) that has been of most use to man. A succulent plant with thick fleshy leaves which conceal an inner gel, it has been used for centuries to maintain health and enhance beauty. Flourishing in warm, dry climate, both the Greeks and the Egyptians valued it highly.

Forever Living Product; www.foreverliving.com

We are the world’s largest growers and producers of Aloe Vera and have a patented stabilization process ensuring ours is essentially identical to the inner leaf gel. Freshness is therefore assured. Our Aloe is also free from herbicides, pesticides, pasteurization, freeze drying and heat treatment.

Aloe Vera is versatile-our wide range includes drinks, health care, skincare, personal care, cosmetics, weight management and all the food supplement your body need. The key to our success it that we don’t simply add a few drops of Aloe Vera to our products, we start with 100% inner gel and just enough other ingredients as needed. Poor diet, stress, caffeine, over-processed foods etc can all lead to less than tip-top health. Aloe, with its wealth of essential nutrient, can help redress the balance. Aloe works with ‘the inner doctor’, our immune system, replenishing the nutrients as requires. Drink anyone of our four options on a daily basis assist digestion and absorption of nutrients, to add vitamin, minerals and amino acids to your diet, and above all a healthy lifestyle. The combination of Aloe Vera with the above named plant will result as a remedy to most common ailment like HIV/AIDS, DIEBETES, KIDNEY STONE, CANCERS, ANXIETY ANGUSH RESTLESSNESS, ASTHMA, INFERTILY/STERILITY. Ailment like DIABETES, needs, Gin-chia, Aloe Vera Gel, Field of green, Garlic-Thyme, Garcinia plus, forever Lite, and Lycium taken in a directed order will bring the desired result. Give this a try and see for your self. Quote this number 234-000-742-290 when making purchase because you can’t make purchase without it. Visit www.foreverliving.com to make purchase and location the company in your area.

Kingsley lifu, is an internet health care security consultant, and a distributor of for-ever living health care, nutritional, skin, beauty care, weight management and food supplement product, www.healthcaresecurity.blospot.com (www.foreverliving.com) with I D number 234-000-742-290, also a writer on how to get rich beyond your limitation, www.gettingrichesbeyondlimit.blogspot.com

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Yamaha Musical Keyboard – What is a suitable keyboard for Beginner?

31 Jul

Yamaha Musical Keyboard – What is a suitable keyboard for Beginner?

If you have decided to buy your first musical keyboard from yamaha, then here is what you need to consider. Yamaha has a wide range of keyboards suitable for beginners, intermediate as well as advanced players, so it can get difficult to focus on what you want.

You need to go in for a Yamaha keyboard that has touch response keys. An important aspect of learning to play keyboards is to play it with expression, and not just in a monotonous way. Touch sensitive keys are a must for that reason because then not all notes are played with the same volume, you can change it by applying different force. Besides, a keyboard with touch response keys also teaches your fingers to have better control over the keys.

Another thing is to buy a Yamaha keyboard that has at least sixty-one keys. This is important if you want to seriously learn the keyboard. If you go in for a keyboard with lesser number of keys, you will nit be able to use your left hand. That means you will not be able to learn and play chords together with the melody; though you can learn the basics like learning to play the notes and timing, you will not be able to learn to harmonize.

So what are the options? Yamaha YPT, PSR and lighted series keyboards are something that you can consider. You may even consider used-keyboard if you are on a tight budget. Cost is obviously an important aspect to keep in mind.

It should not be a problem to use a pre-owned keyboard since Keyboards generally last for many years. You should even consider having a look at if you want something that is a bit cheaper.

Yamaha Keyboard Reviews

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The Synthesis Methods of Sound

31 Jul

The Synthesis Methods of Sound

Sound synthesis refers to the creation of interesting sounds using artificial means. The word artificial is referring to the creation of the sound by man. In a sense, sound synthesis has been going on for a long time, and what are considered by many today to be natural instruments are in fact examples of sound synthesis.


Most people consider synthetic sounds to be those produced through the use of electronic devices, and as digital sound synthesis grew of the these techniques, such will be referred to as synthetic sounds. Special sound effects are an important matter associated with sound synthesis because almost all synthesis methods use some sort of wave form as a base and modify it to create the desired sound.


A brief history of sound synthesis methods


One of the earliest devices used in sound synthesis was the tape recorder. The first use of the tape recorder apart from recording was to splice different pieces of composition together. Another early use of the tape recorder was to change the pitch and speed of a recorded piece. This was done by changing the playback speed of the recorded music, although such changes also affected the duration of the recording. After the tape recorder, the next major step in sound synthesis was the use of analog circuits, such as oscillators, op-amps, resistors, capacitors, inductors, and filters to create sounds. One early idea behind many analog synthesis methods was to take a source signal, either a recorded sound or one generated using oscillators, and to filter this signal, perhaps providing a feedback loop to control the generated signal. A variety of filters and envelopes were used to eliminate unwanted harmonics, and to modify the relative amplitudes. The adaptation of digital technology to sound synthesis was the next big step. Digital methods offered advantages over analog methods because of several factors.


Some general points about good synthesis methods


The best methods of synthesis are generally based on tried and true principles. A good synthesizer must have facilities to do what it was designed for. When using a synthesizer in a performance situation, real time control facilities should be paramount.


Sound synthesis methods


Of the many techniques developed for sound synthesis, an important one is FM or frequency modulation. This is because it allows for the generation of a wide variety of sounds, using a small number of parameters. After a suitable starting signal or FM has been generated filters and envelopes are used to take away the unwanted components of a sound while synthesizing sound. The frequency content determines what a synthesis sound will sound like.


An early idea was to take white noise, and filter out all of the unwanted components until only the desired components remain. This method of subtractive sound synthesis proved difficult to do because of limitations of filters.


A much better approach is to generate a sound with the desired components already present, as well as some unwanted components, and to use filters to remove only the unwanted components, as well as to adjust the relative frequency content. The final step in getting realistic sounds using synthesis is to simulate some special effects.


One of the most basic effects is reverberation. Reverberation can be created by adding a time delayed version of the original signal to itself. The relative magnitudes of how the two are mixed determine the amount of reverberation is present.

Victor Epand is an expert consultant for guitars, drums, and synthesizers. You can find the best marketplace for guitars, drums, and synthesizers at these 3 sites: guitars, bass guitar gears , drums, drum sets, drum kits, and synthesizers, keyboards, filters.

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How to Fix Your Keyboard Problems

31 Jul

How to Fix Your Keyboard Problems

A keyboard is a very important input device in a computer. When you buy a computer you have to equip it with a keyboard. Though you can boot up your machine, without a keyboard you have no way to input characters and password, or change settings, etc. And it would also be damaged during using.

Some of the common problems are:

1. “Keyboard error or not present” on start, and keyboard does not response no matter which key you press down.

2. Computer prompts on start: “Keyboard error: press F1 to continue”.
3. Blank screen on start and the PC will have a sound like “tick” when you press a key.
4. Computer can not enter its operating system or only can enter its Safe Mode when connected a keyboard.

5. The keys do not strike correctly.

6. You can operate your PC normally, but when you press a key, you will hear a “tick” in this machine.

7. Black screen on start and its three lights flicker regularly.

When you try to locate the keyboard problems, you should also observe the state of its three lights: “Num Lock”, “Caps Lock”, and “Scroll Lock”. If they all flicker in the meantime, usually it indicates that probably the MCU circuit in this device is damaged; if these lights are being off all the time, may be you haven’t connected your keyboard correctly or its cable is broken.

Solutions:

1. Make sure the keyboard connector and its port on the motherboard have not been distorted and they are connected securely.

2. Install another good keyboard onto your computer. If the failure still continues, the connecting port on your main board may be damaged, and you need to repair it or swap a new one. But if this failure disappears, well then possibly your primary keyboard’s cable is damaged and you need to replace it, or some part like a switch on the device’s electric circuit is mangled so you need to repair it or buy a new one if necessary.

3. Uninstall, reinstall or update your keyboard drivers. You can download a driver tool like Driver Checker to help you manage your keyboard driver automatically.

4. If you spilled some water or liquid into this device by accident, you can take it apart and clean the water, liquid or other dirt there with some alcohol. If it does not work, buy a new one.

5. Use a USB keyboard if possible.

Click here for a FREE SCAN to find what problem your keyboard has.

The author, Molly Smith, is an expert of device driver problems repair and PC optimization. Do visit http://www.driverchecker.com/ for more free and useful information.

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Savage Garden Affirmation Pop Music CD Review

30 Jul

Savage Garden Affirmation Pop Music CD Review

Affirmation is the latest Pop CD released by the extremely group Savage Garden and they have once again delivered a brilliant collection of tracks. I’m confident Savage Garden fans, and Pop fans alike will be pleased with this one.

Refreshingly, this was one of those CDs I was able to just pop in and comfortably listen to from beginning to end. Every track is enjoyable and was pretty easy for me to listen to from start to finish.

The nice thing about a CD like this is when the talent is this rich even if Pop isn’t your favorite style you still can’t help but appreciate the greatness of the musicians.

Overall Affirmation is excellent from beginning to end. One of those CDs that after a few listens the songs are just etched into your memory. A must have for the Pop fan. Really spectacular from beginning to end.

While this entire album is really very good the truly standout tunes are track 3 – I Knew I Loved You, track 9 – Two Beds And A Coffee Machine, and track 12 – I Don’t Know You Anymore.

My Bonus Pick, and the one that got Sore [...as in "Stuck On REpeat"] is track 1 – Affirmation. What a nice track!

Affirmation Release Notes:

Savage Garden originally released Affirmation on November 9, 1999 on the Columbia label.

CD Track List Follows:

1. Affirmation 2. Hold Me 3. I Knew I Loved You 4. Best Thing, The 5. Crash And Burn 6. Chained To You 7. Animal Song, The 8. Lover After Me, The 9. Two Beds And A Coffee Machine 10. You Can Still Be Free 11. Gunning Down Romance 12. I Don’t Know You Anymore

Savage Garden: Darren Haynes (vocals); Daniel Jones (electric guitar, keyboards, synthesizer, programming).

Additional personnel includes: Jeremy Lubbock (conductor); Dean Parks (acoustic guitar); Michael Thompson (electric & baritone guitars); Michael Landau (electric guitar); Walter Afanasieff (piano, keyboards, synthesizer, programming); Greg Bieck (keyboards, synthesizer, programming); Nathan East (bass); Steve Smith (drums); Adam Rossi, Dan Shea (programming). Engineers include: Kent Matcke, Jay Healy, David Reitzas.

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Intellivision: a Game Console Far Ahead of Its Time

30 Jul

Intellivision: a Game Console Far Ahead of Its Time

The Intellivision was a revolutionary video game console developed and released by Mattel (the company probably best known for Barbie dolls, Hot Wheels and Matchbox cars) in 1979. It was the first 16 bit game console ever released and introduced a lot of new concepts and technologies: innovative game controllers, superior graphics and sound, game downloads, home computer extensions, a voice synthesis device and a synthesizer keyboard for example.

The CPU used in the Intellivision was a General Instruments CP1610, a general purpose microprocessor capable of supporting 16-bit addresses and 10-bit instructions. The US release used a CPU clock of 894,886.25 Hz while the european release used a 1 Mhz clock, due to the different NTSC / PAL specs, which means that games were running up to 10% faster on european consoles than on their US counterparts!

The CP1610 featured eight 16-bit registers – using a 16 bit CPU in a video game console was quite exceptional indeed. It had 1.2 kb of RAM (including 512 byte video memory) and 7 kb ROM (which included the “Executive ROM” – some kind of a mini-OS – and the “Graphics ROM” which included often used sprites for example). It’s graphics performance was outstanding for the late 1970′s, allowing a 160 x 196 pixel display using a 16 color palette (all colors could be used simultaneously), plus eight hardware supported sprites offering collision detection, mirroring and streching.

The game controllers were quite different too, as they featured a “disc” (somewhat similar to the Apple iPod clickwheel) instead of a joystick as well as a twelve-button numeric keypad. The disc was capable of 16 direction detection and games usually shipped with “overlay cards” that could be inserted into the controllers (in front of the numeric keypad – switching games required inserting a new cartridge AND flipping the overlay cards).

In 1980 the Intellivision became available in the entire US for US9, the console was the first to pose a serious threat to Atari’s dominance (Atari was the number one video game console producer back then). Mattel sold 175,000 consoles in 1980, with 19 availalble games. After Mattel realized that the game market offered good revenues, they launched their own software development group which became known as the “Blue Sky Rangers”.

In 1981, Mattel launched a service that allowed to download games via cable TV. In 1982, Mattel sold 2 million consoles, more and more companies started developing software titles for the Intellivision.

The “Keyboard Component” should transform the console into a home computer, it was planned to include a MOS 6502 CPU (the one used by the C64 later on), 64K RAM and a built-in cassette tape drive. But during the process of developement many reliability problems occurred and the hardware was far too expensive. After repeated delays the Keyboard Component project was officially cancelled in 1982. Apparently about 4000 Keyboard Components had been shipped to selected customers for testing purposes, they are extremely rare today.

As Mattel managers had been aware of the Keyboard Component problems for a long time, they had launched a secondary project in mid 1981 that could replace the component in case of a complete failure. It was released as Entertainment Computer System (ECS), it featured a keyboard with a cassette recorder interface and included 2k of additional RAM. It lacked the originally planned 6502 CPU and the 64K RAM extension, but it was functionalm cost effective and was finally able to turn the Intellivison into a home computer.

Shortly after, Mattel introduced a 49-key Music Synthesizer keyboard which could turn the Intellivision/ECS combo into a multi-voice synthesizer. Unfortunately, the ECS received very little further marketing push and further hardware and software developments for the ECS were cancelled.

Intellivision was also the first game console to provide real-time human and robot voices during game play. The IntelliVoice module, which was required for using this feature, used an SP0256 Orator “voice chip” developed jointly by Mattel and General Instrument. But the IntelliVoice didn’t sell as well as expected, and only a few games supporting it were ever released.

In 1983 Mattel also introduced the Intellivision II (which only introduced a revamped case) and the System Changer module (which allowed to play Atari 2600).

In 1983 and 1984 the video game market crashed. The new home computer systems became more and more popular and interest in classic game consoles vanished. Furthermore there was now a large number of video game consoles available, further subdividing the market. In 1983 Mattel Electronics posted a 0 million loss, in early 1984 the division was closed.

A liquidator purchased all rights, hardware and software sales continued until most of the inventory had been sold. Later on, Mattel Marketing executive Terry Valeski created INTV Corp. which sold the remaining stock via retail and mail order. They then introduced the INTV III, which was nothing but an Intellivison inside a new case, and continued developing a few games. The console was discontinued in 1991. More than 6 million Intellivision consoles were sold during 12 years, and a total of 125 games were available.

Keith Robinson, a former Mattel programmer, finally purchased the software rights, founded Intellivision Productions and released Intellivison emulators including the classic Intellivision games available for MacOS, Windows and modern-day consoles.

Jos Kirps is the creator of several software and web projects, including Galaxiki, a science fiction galaxy where site members can get their own solar system and the Joopita.com web directory and search engine.

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